سطح پلاسمایی ویسفاتین زنان مبتلا به دیابت نوع 2: مقایسه اثر دو نوع پروتکل تمرینی هوازی و مقاومتی

    Introduction : visfatin is a protein with insulin-like functions that secretes from adipose tissue and has been linked to obesity and insulin resistance, but the effect of exercise training on visfatin levels is unknown. The purpose of study was to compare the effect of aerobic and resistance training on plasma visfatin levels in type 2 diabetic women.   Material and Methods : 45 women with type 2 diabetes were selected by purposive sampling and subjects were randomly assigned in 3 groups.15 subject participated in an aerobic training (3 days/week, 20-50 min/day, 60-80% maximum heart rate), 15 subject participated in a resistance training (3days/week, 60 min/day,3 sets of 10 repetition,50-65% 1RM), and 15 subject were in control group who did not participate in any exercise program during the study periode. blood samples were collected for assess plasma visfatin, insulin, HbA1c and glucose levels before anf after 12 weeks of the training program and insulin resistance was calculated with HOMA-IR equation.   Result : Data analysis showed that aerobic training leads to significant decrease in visfatin concentration (p=0/04), whereas resistance training enhanced visfatin concentration (p=0/13). Also there was a significant decrease in glucose, HbA1c, insulin resistance, body mass index, waist-hip ratio and %body fat in experimental groups as compared with control group (p≤0/05).   Conclusion : The aerobic exercise training-induced reduction of plasma visfatin is most likely the result of decrease in Anhtropometric and Glycemic indices and nonsignificant enhance insulin levels in type 2 diabetes women.    SOURCE: URMIA MED J 2014: 25(2): 159 ISSN: 1027-3727